sp78428.exe is part of a product called known as AMD Graphics Driver for R5 320 1G and the developer is Hewlett-Packard Company .
If you think that this file contains a virus or another malware, please download a virus scanner.
If sp78428.exe is using too much CPU or too much memory in your system, it is possible that your file has been infected with a virus. Installing an antivirus is recommended.
Not all processes can be uninstalled without the help of a 3rd party tool, especially malware. To see if it can be uninstalled, first go to Start > Control Panel > Add/Remove programs and select AMD Graphics Driver for R5 320 1G from the list to remove the process sp78428.exe from your computer.
If you have any problems with sp78428.exe, you may try using a registry cleaner or a speed-up software to check, analyze, and fix problems that are affecting the performance of your computer.
You may try contacting Hewlett-Packard Company, the developer of sp78428.exe and ask for more information.