NSMBW Setup.exe is part of a product called known as New Super Mario Bros. Wii and the developer is BlizzBoyGames - https://www.blizzboygames.net .
If you think that this file contains a virus or another malware, please download a virus scanner.
If NSMBW Setup.exe is using too much CPU or too much memory in your system, it is possible that your file has been infected with a virus. Installing an antivirus is recommended.
Not all processes can be uninstalled without the help of a 3rd party tool, especially malware. To see if it can be uninstalled, first go to Start > Control Panel > Add/Remove programs and select New Super Mario Bros. Wii from the list to remove the process NSMBW Setup.exe from your computer.
If you have any problems with NSMBW Setup.exe, you may try using a registry cleaner or a speed-up software to check, analyze, and fix problems that are affecting the performance of your computer.
You may try contacting BlizzBoyGames - https://www.blizzboygames.net, the developer of NSMBW Setup.exe and ask for more information.